MyBioSource.com's Ankyrin B Antibody: FITC is a Mouse monoclonal antibody. The Ankyrin B Antibody: FITC was generated using ANK2, and Ankyrin B as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Background Info: Detects ~200kDa. No cross-reactivity against Ankyrin-G
Scientific Background: Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane